5-Amino-1MQ
Lyophilized research reference material. Released with a per-lot Certificate of Analysis. For laboratory research use only.
- All products currently listed on this site are for research purposes ONLY.
- All products sold on this website are intended for research and identification purposes only.
- These products are not intended for human dosing, injections, or ingestion.
- Peptides are strictly for laboratory, academic, or institutional research and not for human or animal consumption.
Research background
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme implicated in cellular methylation balance and NAD+ salvage. Research examines NNMT inhibition in models of adipocyte metabolism.
The data are preclinical (cell and rodent); 5-Amino-1MQ is a research chemical without an approved indication.
Summary of published scientific literature provided for laboratory research reference only. It is not a claim of safety, efficacy, or suitability for any use, and does not describe or recommend any human or veterinary use.
Selected references
- Neelakantan H, et al. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse diet-induced obesity in mice. Biochemical Pharmacology. 2018;147:141-152.
- Kraus D, et al. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 2014;508(7495):258-262.
- Pissios P. Nicotinamide N-methyltransferase: more than a vitamin B3 clearance enzyme. Trends in Endocrinology & Metabolism. 2017;28(5):340-353.
Trademarks & attribution
5-Amino-1MQ is a research chemical (NNMT inhibitor) with no registered pharmaceutical trademark or approved drug product. Supplied as reference material only.
