SNAP8
Peptide researched for muscle relaxation and skin appearance.
SNAP8
Background
SNAP-8 (acetyl octapeptide-3) is a synthetic peptide developed as an elongated analog of the cosmetic peptide Argireline. It is studied for its proposed ability to interfere with assembly of the SNARE complex involved in neurotransmitter vesicle docking, with the aim of attenuating muscle contraction relevant to expression lines.
The mechanism is extrapolated from work on the parent acetyl hexapeptide; evidence is largely formulation-based and cosmetic in nature.
Selected literature
- Blanes-Mira C, et al. A synthetic peptide that inhibits neurotransmitter release. International Journal of Cosmetic Science. 2002;24(5):303-310.
- Lima TN, Pedriali Moraes CA. Bioactive peptides: applications and relevance for cosmeceuticals. Cosmetics. 2018;5(1):21.
- Reddy B, et al. Topical peptides in cosmetic formulation: a review. Journal of Cosmetic Dermatology. 2012.
References are provided for scientific context only. Citation does not imply endorsement of any use, nor a claim of safety or efficacy. Findings frequently derive from in-vitro or animal models.
Trademarks & attribution
SNAP-8 (acetyl octapeptide-3) is a cosmetic peptide; related formulations are marketed under proprietary names owned by their manufacturers (for example by Lipotec/Lubrizol). The compound itself is supplied as reference material only. Catalyst Research Labs is not affiliated with those manufacturers.
