Semax
Lyophilized research reference material. Released with a per-lot Certificate of Analysis. For laboratory research use only.
- All products currently listed on this site are for research purposes ONLY.
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- These products are not intended for human dosing, injections, or ingestion.
- Peptides are strictly for laboratory, academic, or institutional research and not for human or animal consumption.
Research background
Semax is a synthetic peptide based on a fragment (residues 4-10) of adrenocorticotropic hormone modified for metabolic stability. It has been studied for neuroprotection- and cognition-related effects, with proposed mechanisms including regulation of BDNF and its receptor TrkB and modulation of monoaminergic signaling.
The research literature, largely Russian in origin, includes rodent models of cerebral ischemia and cognition. Evidence remains predominantly preclinical.
Summary of published scientific literature provided for laboratory research reference only. It is not a claim of safety, efficacy, or suitability for any use, and does not describe or recommend any human or veterinary use.
Selected references
- Dolotov OV, et al. Semax, an analog of ACTH(4-10), regulates BDNF and trkB expression in the rat hippocampus. Brain Research. 2006;1117(1):54-60.
- Medvedeva EV, et al. The peptide semax affects gene expression related to the immune and vascular systems in rat brain. Molecular Biology. 2014;48(3):373-382.
- Ashmarin IP, et al. Semax: development and study. Voprosy Meditsinskoi Khimii. 1997;43(5):331-337.
Trademarks & attribution
Semax was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It has no registered Western pharmaceutical trademark or approved drug product. Catalyst Research Labs is not affiliated with that institute. Supplied as reference material only.
